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Mantle cell lymphoma
3 associated genes
7 signs/symptoms
PROTEIN INTERACTIONS: 1
Desmoid tumor
1 OMIM reference -
2 associated genes
21 signs/symptoms
Mantle cell lymphoma
Desmoid tumor

ATM
(UniProt - OMIM)
 APC
(UniProt - OMIM)
CCND1
(UniProt - OMIM)
 CTNNB1
(UniProt - OMIM)
IGH
(UniProt)

INTERACTOME
ASSOCIATIONS
(click on a score value to see the evidence)
CCND1
(0.62)
CTNNB1


Citations in the biomedical literature:


Mantle cell lymphoma
ATM CCND1 IGH
Desmoid tumor
APC CTNNB1



Mantle cell lymphoma
Desmoid tumor

Synonym(s):
- LCM
- MCL
- Mantle zone lymphoma
Synonym(s):
- Aggressive fibromatosis
- Desmoid type fibromatosis
Classification (Orphanet):
- Rare hematologic disease
- Rare oncologic disease
Classification (Orphanet):
- Rare oncologic disease
Classification (ICD10):
- Neoplasms -
Classification (ICD10):
- Neoplasms -
Epidemiological data:
Class of prevalence: 1-9 / 100 000
Average age onset: adulthood
Average age of death: adult
Type of inheritance: multigenic/multifactorial
Epidemiological data:
Class of prevalence: unknown
Average age onset: adolescence / young
Average age of death: normal
Type of inheritance: sporadic
External references:
No OMIM references
1 MeSH reference: D020522
External references:
1 OMIM reference -
No MeSH references
Mantle cell lymphoma
Desmoid tumor

Very frequent
- Hematologic / blood / lymphatic cancer
- Lymphadenopathy / polyadenopathies

Frequent
- Anorexia
- Asthenia / fatigue / weakness
- Bone marrow / medullar infiltration
- Splenomegaly
- Weight loss / loss of appetite / break in weight curve / general health alteration



Very frequent
- Anomalies of the abdominal wall
- Fibromatosis / bone fibroma
- Muscle anomalies
- Soft tissue sarcoma / cancer / tumor / liposarcoma / myosarcoma
- Subcutaneous nodules / lipomas / tumefaction / swelling

Frequent
- Acute abdominal pain / colic
- Myalgia / muscular pain
- Polyposis of the bowel / colon / intestine

Occasional
- Articular / joint pain / arthralgia
- Bladder and ureter anomalies
- Early death / lethality
- Gastrointestinal bleeding / hemorrhage / hematemesis / melena / rectorrhagia
- Intestinal obstruction / ileus
- Malabsorption / chronic diarrhea / steatorrhea
- Megaureter / hydronephrosis / pyeloureteral junction syndrome
- Osteolysis / osteoclasia / bone destruction / erosions
- Restricted joint mobility / joint stiffness / ankylosis
- Retinitis pigmentosa / retinal pigmentary changes
- Sepsis severe / septicemia
- Skin tumors / lumps / epidermal cysts
- Thoracic / chest pain